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Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file. Получить ссылку |
Testing SAP R/3
A Manager’s Step-by-Step Guide
Автор: JOSE FAJARDO, ELFRIEDE DUSTIN
Год издания:
Planning, preparing, scheduling, and executing SAP test cycles is a
time-consuming and resource-intensive endeavor that requires participation
from several project members. SAP projects are prone to
have informal, ad-hoc test approaches that decrease the stability of
the production environment and tend to increase the cost of ownership
for the SAP system. Many SAP project and test managers cannot
provide answers for questions such as how many requirements have
testing coverage, the exit criteria for a test phase, the audit trails for
test results, the dependencies and correct sequence for executing test
cases, or the cost figures for a previously executed test cycle. Fortunately,
through established testing techniques predicated on guidelines
and methodologies (i.e., ASAP SAP Roadmap methodology,
IBM’s Ascendant methodology, and Deloitte’s ThreadManager
methodology), enforcement of standards, application of objective
testing criteria, test case automation, implementation of a requirements
traceability matrix (RTM), and independent testing and formation
of centralized test teams, many of the testing risks that plague
existing or initial SAP programs can be significantly reduced.
This book is written for SAP managers, SAP consultants, SAP
testers, and team leaders who are tasked with supporting, managing,
implementing, and monitoring testing activities related to test planning,
test design, test automation, test tool management, execution of
test cases, reporting of test results, test outsourcing, planning a budget
for testing activities, enforcing testing standards, and resolving
defects.
Oracle Database 10g: A Beginner's Guide
Автор:
Год издания:
Two new Oracle instruction and resource titles from Osborne/McGraw-Hill are indispensable additions to personal and professional reference collections. Oracle Database 10g: A Beginner's Guide is the collective effort of Oracle experts Ian Abramson, Michael Abbey and Michael Corey. Oracle Database 10g provides neophytes with the fundamental concepts of Oracle Database 10g administration and programming. Through self-paced tutorials, readers will learn about database essentials, the role of the administrator, and large database features. Oracle Database 10g includes an in-depth introduction to SQL, PL/SQL, Java, and XML programming.
Fiat Tipo and Tempra 1988-1996. Repair Manual – service guide
Автор: Коллектив авторов
Год издания:
Инструкция по ремонту и обслуживанию моделей Fiat Tipo и Tempra. Дано описание всех узлов и агрегатов и советы по их эксплуатации и техобслуживанию. Чертежи, таблицы и схемы электрооборудования.
Fiat Tipo - автомобиль итальянской компании Фиат. Был разработан дизайн студией IDEA. Выпускался с 1988 года по 1996 год.
Guide to self-repairing car bodies, in eBook
Автор: Монолит
Год издания:
Content
Introduction
- Body / frame and body structure
- General information about replacing body panels
- Safety first
Maintenance
- Caring for paint
- Recovery
- Antirust treatment and priming
Overview of damage types and their recovery
- Determination of severity of damage
- The choice between repair and replacement
Tools and equipment
- Tools and equipment
- Equipment
Elimination of minor body damage
- Eliminating scratches from paintwork
- Elimination of minor dents
- Restoration of areas exposed to minor corrosion
- Repair of plastic body parts
Restoring a body that has serious damage
- Types of tin work
- Putties
- Correction of significant corrosion damage
- Glass fiber recovery methods
- Correcting the stiffness of the bearing body by stretching
Replacement of body panels
- Introduction
- Body parts fastened on bolts
- Welded panels
- Adhesive body elements
- Coupling of body panels
Preparing for painting
- Preparation of old paint
- Removing paintwork preparing for painting
- Application of primer
- Masking panels
Body painting
- Painting equipment
- Maintenance of the spray gun
- Types of paint
- Staining procedure
- Prophylaxis and a technique of elimination of the defects arising at painting and drying
Doors and glasses
- Replacement and adjustment of doors
- Repair, replacement and installation of glasses
Facing and body accessories
- General information
- Removing and installing body linings and accessories
- Removing and installing outdoor lighting
- Removing and installing emblems and moldings
Welding
- General information
- Types of welding
- Welding with a consumable electrode in shielding gas
- Oxygen-acetylene welding
- Soldering
A dictionary of terms used in the performance of body repair
Welding guide, in eBook
Автор: Монолит
Год издания:
Content
Introduction
- Definition of the welding process
- Development of modern welding
- Welding these days
Types of welding
- How it works
- Metal alloys
- Oxygen-acetylene welding
- Electric arc welding
- Apparatuses for arc welding with a consumable electrode in an inert gas environment
- Arc welding with tungsten electrode in an inert gas environment
- Work cycles
- Plasma welding and cutting
- Practice and training
Oxygen-acetylene welding / cutting
- Basics of gas welding technology
- Equipment
- Getting Started with oxygen-acetylene welding equipment
- Flame adjustment
- Gas welding
- Welding with filler rod
- Inspection of welds
- Soldering
- Oxygen-acetylene cutting
- Heating with an oxygen-acetylene burner
Electric arc welding
- Comparison of work cycles
- Units working on AC, DC or universal?
- Arc welding technology
- Precautions
- Start of electric arc welding
- Connection types
- Electrode selection
Welding with a metal electrode in an inert gas environment
- Acquisition of aggregates for welding with a metal electrode in an inert gas environment
- Selection of shielding gas
- Selecting a wire electrode
- Welding training with a metal electrode in an inert gas environment
Welding with a tungsten electrode in an inert gas environment
- Equipment
- Technology in action
- Aluminum welding with tungsten electrode in an inert gas environment
Plasma welding / cutting
- Plasma welding
- Plasma cutting
- Selection of equipment for plasma cutting
- Using plasma cutting
Safety and equipment for the workshop
Making a truck trailer to a car
Glossary of terms related to welding