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A valuable reference tool for professionals involved in the industry, Drug Metabolism in Pharmaceuticals covers new tools such as LC-MS and LC-MS-NMR along with experimental aspects of drug metabolism. This work fills a gap in the literature by covering the concepts and applications of pharmaceutical research, development, and assessment from the point of view of drug metabolism. By providing both a solid conceptual understanding of the drug metabolism system, and a well illustrated, detailed demonstration and explanation of cutting edge tools and techniques, this book serves as a valuable reference tool for bench scientists, medical students, and students of general health sciences.

Epidemiology Kept Simple introduces the epidemiological principles and methods that are increasingly important in the practice of medicine and public health. With minimum use of technical language it fully explains terminology, concepts, and techniques associated with traditional and modern epidemiology. Topics include disease causality, epidemiologic measures, descriptive epidemiology, study design, clinical and primary prevention trials, observational cohort studies, case-control studies, and the consideration of random and systematic error in studies of causal factors. Chapters on the infectious disease process, outbreak investigation, and screening for disease are also included. The latter chapters introduce more advanced biostatistical and epidemiologic techniques, such as survival analysis, Mantel-Haenszel techniques, and tests for interaction. This third edition addresses all the requirements of the American Schools of Public Health (ASPH) Epidemiological Competencies, and provides enhanced clarity and readability on this difficult subject. Updated with new practical exercises, case studies and real world examples, this title helps you develop the necessary tools to interpret epidemiological data and prepare for board exams, and now also includes review questions at the end of each chapter. Epidemiology Kept Simple continues to provide an introductory guide to the use of epidemiological methods for graduate and undergraduate students studying public health, health education and nursing, and for all practicing health professionals seeking professional development.

The facts about Lyme disease, from epidemiology to treatment to control Lyme borreliosis, popularly known as Lyme disease, remains the most commonly reported tick-transmitted infection in North America and Europe. A growing body of scientific and clinical evidence has facilitated early diagnosis and effective treatment. Nonetheless, there are a number of misconceptions about this infectious disease that have given rise to unproven, potentially dangerous alternative therapies. In Lyme Borreliosis in Europe and North America, a team of authors whose expertise spans basic research, epidemiology, and clinical practice has compiled evidence-based information on Lyme borreliosis. Presents all the latest evidence needed to diagnose, treat, and prevent Lyme disease Lyme Borreliosis in Europe and North America begins with a review of the disease's epidemiology, the causative Borrelia genospecies, and tick vectors. It then explores pathogenesis, diagnosis, and treatment. Next, the book examines the role of serologic, culture, and molecular diagnostic methods. The book also features a chapter on prognosis, offering an evidence-based review of outcome studies, as well as practical advice to physicians to help them manage the challenging clinical scenario of chronic symptoms attributed to Borrelia infection. The final chapter is a guide to prevention strategies, including the management of tick bites. Examines similarities and differences in Europe and North America Because differences in Borrelia genospecies are responsible for differences in the clinical presentation of Lyme borreliosis between North America and Europe, this book provides descriptions of the disease as it presents on each continent. Most of the chapters have been cowritten by experts on each continent, in order to provide a balanced perspective that combines European and North American findings, practices, and experiences. Helps everyone better understand, treat, and control Lyme disease Lyme Borreliosis in Europe and North America is a comprehensive reference, ideal for clinicians, researchers, and public health officials who seek to treat and control Lyme borreliosis. It will help them better understand the facts and make sense of the misconceptions and myths that surround this infectious disease.

Written by Peter J. Fos—an expert in epidemiology with more than twenty years teaching experience—Epidemiology Foundations offers an ideal introduction to the theory and practice of public health epidemiology. This important text discusses both the historical perspective and future trends of epidemiology, reviews health and disease, and explains how they are measured. The book's overview of epidemiological studies shows how they are used in practice. Epidemiology Foundations takes a social and community perspective and includes information about global diseases and epidemics. Emphasis on concepts such as population health, social determinants, and global health make this book especially interesting and accessible to those new to the subject. Each chapter is supplemented with problem-solving exercises and research assignments to aid readers in understanding its epidemiology principles. Reflecting and expanding on recommendations of the Association of American Colleges and Universities, Epidemiology Foundations is the ideal text for any course introducing epidemiology in public health.

This brand new Annual Plant Reviews volume is the second edition of the highly successful and well-received Annual Plant Reviews, Volume 2. This exciting new volume provides an up-to-date survey of the biochemistry and physiology of plant secondary metabolism. The volume commences with an overview of the biochemistry, physiology and function of secondary metabolism, followed by detailed reviews of the major groups of secondary metabolites: alkaloids and betalains, cyanogenic glucosides, glucosinolates and nonprotein amino acids, phenyl propanoids and related phenolics, terpenoids, cardiac glycosides and saponins. A final chapter discusses the evolution of secondary metabolism. This carefully compiled new edition brings together chapters from some of the world's leading experts in plant secondary metabolism. Completely revised and brought right up to date with much new information, this volume is an essential purchase for advanced students, researchers and professionals in biochemistry, physiology, molecular biology, genetics, plant sciences, agriculture, medicine, pharmacology and pharmacy, working in the academic and industrial sectors, including those working in the pesticide and pharmaceutical industries. Libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves. A companion volume Annual Plant Reviews Volume 39, Functions and Biotechnology of Plant Secondary Metabolites, Second Edition, Edited by M. Wink, is also available.