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Praise For Toxic People «From corporate America to the smallest business owner, this book should be mandatory reading because it provides toxic relief that will put money in your pocket and calm in your personality. A dose of this reading would enhance the success of business school students and smooth out a few bumps in a rocky marriage.» —Richard L. Labrum, Vice President, Wealth Management, Smith Barney «If you're just sick to death of those people who zap the energy right out of you, Marsha has the cure! In no-nonsense terms, she gives us the prescription for dealing with toxic people. She mixes in the right dosage of personal experience, humor, and practical advice to create a compelling message that is highly relevant in our personal and professional lives. I highly recommend this book to everyone interested in cleaning up toxic behaviors!» —John Ryan, Vice President, American Express «Marsha Petrie Sue is the Muhammad Ali of communicators. She can dance and look pretty, and she uses the entire ring, but she knows how and when to land a knockout punch. If you have bad relationships, you'll learn why. This is charm school with live ammunition!» —David Rawles, founder and President, Career Solutions, Inc. «Marsha Petrie Sue's 'take the bull by the horns' approach to self-realization and, if so chosen, self-improvement, is the antidote to today's wimpy leadership malaise. She takes readers by their collars, looks them straight in the eyes, and tells them in no uncertain terms that their key to both personal and professional happiness is attainable only through critical self-evaluation and the will to transcend their current situations.» —Randy O'Neill, Senior Vice President, Lancer Insurance Company «She has done it again! She gives us permission to 'sack the toxic people' who suck out our energy. Take Marsha's ticket to freedom: give yourself permission to send the toxic people on their not-so-merry way!» —Dr. Geoff Haw, Consultant, Sagacity Services, Australia «Marsha always finds a way to deliver the most difficult messages in a humorous way (this book is one example). You will be able to apply this book in everyday life and anywhere you encounter people!» —Tina Aguirre, Senior IT Manager, oil and energy company

Smoking causes and contributes to a large number of human diseases, yet due to the large number of potentially hazardous compounds in cigarette smoke – almost 5,000 chemicals have been identified, establishing the link between smoking and disease has often proved difficult. This unbiased and scientifically accurate overview of current knowledge begins with an overview of the chemical constituents in cigarette smoke, their fate in the human body, and their documented toxic effects on various cells and tissues. Recent results detailing the many ways components of cigarette smoke adversely affect human health are also presented, highlighting the role of smoking in cardiovascular, respiratory, infectious and other diseases. A final chapter discusses current strategies for the treatment and prevention of smoking-induced illness. Despite the obvious importance of the topic, this is the first comprehensive reference on tobacco smoke toxicity, making for essential reading for all toxicologists and healthcare professionals dealing with smoking-related diseases.

The tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug use For physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a patient is taking the prescribed amount, the drug or dosage is effective, or the prescribed medication is interacting with other drugs can be determined through drug testing. Written as a guide for toxicologists, chemists, and health professionals involved in patient care, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring provides an up-to-date introduction to the tests and methodologies used in a toxicology lab as well as the sources of testing error that can lead to false positives, false negatives, and unreliable conclusions of drug abuse or under use. Covering a host of common therapeutic drugs as well as specific types of interference in immunoassays used in drug testing, the book details a number of possible testing scenarios and problems as well as solutions: False positive results in immunoassays for drugs in abuse testing Interferences in immunoassays used for monitoring anticonvulsants, tricyclic antidepressants, and digoxin False positive alcohol tests using breath analyzers and automated analyzers When a toxicology report is negative in a suspected overdose patient: the world of designer drugs Effects of drug-herb interactions on therapeutic drug monitoring Pharmacogenomics and the general principles of genetic analysis Approaches for eliminating interference/discordant specimen in therapeutic drug monitoring and drugs in abuse testing What to do in case there is no readily available method for testing Complete with easy-to-read tables and flowcharts, this book helps toxicologists, clinical chemists, clinical pathologists, and forensic pathologists develop accurate, unbiased drug monitoring and toxicology reports. Health care professionals involved in patient care, especially of critically ill patients, will find this guide indispensable in making sure lab tests are reliable enough to provide high-quality care. An indispensable handbook to the entire suite of toxicology lab tests, as well as all the possible sources of testing error, Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring offers clear remedies for eliminating and preventing testing error.

Every year throughout the world, individuals’ health is damaged by their exposure to toxic chemicals at work. In most cases these problems will resolve, but many will sustain permanent damage. Whilst any justified claim for compensation requires medical and legal evidence a crucial and often controversial component of this process is the establishment of a causal link between the individual’s condition and exposure to a specific chemical or substance. Causation, in terms of how a substance or substances led the claimant to his or her current plight, can be difficult to establish and the main purpose of this book, is to provide the aspiring expert report writer with a concise, practical guide that uses case histories to illuminate the process of establishing causation in occupational toxicity proceedings. In summary: A practical, accessible guide to the preparation of balanced, scientifically sound expert reports in the context of occupational toxicology. Focuses on the scientist’s role in establishing a causal link between exposure to toxins and an individual’s ill health. Includes real-life case histories drawn from the Author’s 15 years experience in this area to illustrate the principles involved. Expert Report Writing in Toxicology: Forensic, Scientific and Legal Aspects proves invaluable to scientists across a range of disciplines needing guidance as to what is expected of them in terms of the best use of their expertise and how to present their findings in a manner that is authoritative, balanced and informative.