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Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients – in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide. Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.

This book describes basic cell engineering methods, emphasizing stem cell applications, and use of the genetically modified stem cells in cell therapy and drug discovery. Together, the chapters introduce and offer insights on new techniques for engineering of stem cells and the delivery of transgenes into stem cells via various viral and non-viral systems. The book offers a guide to the types of manipulations currently available to create genetically engineered stem cells that suit any investigator's purpose, whether it's basic science investigation, creation of disease models and screens, or cells for therapeutic applications.

Seismic inversion aims to reconstruct a quantitative model of the Earth subsurface, by solving an inverse problem based on seismic measurements. There are at least three fundamental issues to be solved simultaneously: non-linearity, non-uniqueness, and instability. This book covers the basic theory and techniques used in seismic inversion, corresponding to these three issues, emphasising the physical interpretation of theoretical concepts and practical solutions. This book is written for master and doctoral students who need to understand the mathematical tools and the engineering aspects of the inverse problem needed to obtain geophysically meaningful solutions. Building on the basic theory of linear inverse problems, the methodologies of seismic inversion are explained in detail, including ray-impedance inversion and waveform tomography etc. The application methodologies are categorised into convolutional and wave-equation based groups. This systematic presentation simplifies the subject and enables an in-depth understanding of seismic inversion. This book also provides a practical guide to reservoir geophysicists who are attempting quantitative reservoir characterisation based on seismic data. Philosophically, the seismic inverse problem allows for a range of possible solutions, but the techniques described herein enable geophysicists to exclude models that cannot satisfy the available data. This book summarises the author’s extensive experience in both industry and academia and includes innovative techniques not previously published.

“One of the best thrillers I have read this year.” –-Books and Movie Reviews (re Any Means Necessary) In the much-anticipated debut of a new series by #1 bestseller Jack Mars, when elite Delta Force soldier Luke Stone, 29, joins a secretive government agency, he is dispatched on the mission of a lifetime: a whirlwind race across Europe and the Mid-East to save the President’s daughter before she is beheaded by terrorists. In PRIMARY TARGET (Book #1), we see the forging of one of the world’s toughest—and most lethal—soldiers: Luke Stone. A 29 year old veteran who has seen enough battle to last a lifetime, Luke is tapped by the Special Response Team, a secretive new FBI agency (led by his mentor Don Morris) to tackle the most high-stake terrorism operations in the world. Luke, still haunted by his wartime past and newly married to an expecting Becca, is dispatched on a mission to Iraq, with his new partner Ed Newsam, to bring in a rogue American contractor. But what begins as a routine mission mushrooms into something much, much bigger. When the President’s teenage daughter, kidnapped in Europe, is ransomed by terrorists, Luke may be the only one in the world who can save her before it is too late. PRIMARY TARGET is an un-putdownable military thriller, a wild action ride that will leave you turning pages late into the night. It marks the long-anticipated debut of a riveting new series by #1 bestseller Jack Mars, dubbed “one of the best thriller authors” out there. “Thriller writing at its best.” –-Midwest Book Review (re Any Means Necessary) Also available is Jack Mars’ #1 bestselling LUKE STONE THRILLER series (7 books), which begins with Any Means Necessary (Book #1), a free download with over 800 five star reviews!