Скачать книгу - Intracranial Metastases

Intracranial atherosclerosis is the dominant cause of stroke in over 70% of the world’s population. Globalization is leading to an increasingly heterogeneous society everywhere. Advances in imaging techinology allow this previously inaccessible pathology to be clinically studied. Edited by internationally renowned clinicians, Intracranial Atherosclerosis is the first book to examine intracranial causes of stroke. Clinical practice is allied with basic science to guide all those with an interest in stroke on the diagnosis and management of intracranial atherosclerosis.

The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.