Скачать книгу - A Beginner's Guide to Targeted Cancer Treatments



The accessible guide to the principles behind new, more targeted drug treatments for cancer Written for anyone who encounters cancer patients, cancer data or cancer terminology, but have no more than a passing knowledge of cell biology. A Beginner's Guide to Targeted Cancer Treatments provides an understanding of how cancer works and the many new treatments available. Using over 100 original illustrations, this accessible handbook covers the biology and mechanisms behind a huge range of targeted drug treatments, including many new immunotherapies. Dr Vickers translates a complex and often overwhelming topic into something digestible and easily understood. She also explains what cancer is, how it behaves and how our understanding of cancer has changed in recent years. Each chapter takes the reader through how new cancer drugs work and their benefits and limitations. With the help of this book, readers will be able to better understand more complex, in-depth articles in journals and books and develop their knowledge. This vital resource: Offers the latest insights into cancer biology Provides a broad understanding of how targeted cancer treatments work Describes many of the new immunotherapy approaches to cancer treatment, such as checkpoint inhibitors and CAR-modified T cells Helps readers feel confident discussing treatment options with colleagues and patients Provides an overview of which treatments are relevant to each of the most common solid tumours and haematological cancers, and the rationale behind them Demystifies the jargon – terms such as the EMT, cancer stem cells, monoclonal antibodies, kinase inhibitors, angiogenesis inhibitors etc. Explains the resistance mechanisms to many new treatments, including issues such as the way cancer cells diversify and evolve and the complex environment in which they live


Testing SAP R/3
A Manager’s Step-by-Step Guide Testing SAP R/3 A Manager’s Step-by-Step Guide

Автор: JOSE FAJARDO, ELFRIEDE DUSTIN

Год издания: 

Planning, preparing, scheduling, and executing SAP test cycles is a time-consuming and resource-intensive endeavor that requires participation from several project members. SAP projects are prone to have informal, ad-hoc test approaches that decrease the stability of the production environment and tend to increase the cost of ownership for the SAP system. Many SAP project and test managers cannot provide answers for questions such as how many requirements have testing coverage, the exit criteria for a test phase, the audit trails for test results, the dependencies and correct sequence for executing test cases, or the cost figures for a previously executed test cycle. Fortunately, through established testing techniques predicated on guidelines and methodologies (i.e., ASAP SAP Roadmap methodology, IBM’s Ascendant methodology, and Deloitte’s ThreadManager methodology), enforcement of standards, application of objective testing criteria, test case automation, implementation of a requirements traceability matrix (RTM), and independent testing and formation of centralized test teams, many of the testing risks that plague existing or initial SAP programs can be significantly reduced. This book is written for SAP managers, SAP consultants, SAP testers, and team leaders who are tasked with supporting, managing, implementing, and monitoring testing activities related to test planning, test design, test automation, test tool management, execution of test cases, reporting of test results, test outsourcing, planning a budget for testing activities, enforcing testing standards, and resolving defects.


Oracle Database 10g: A Beginner's Guide Oracle Database 10g: A Beginner's Guide

Автор: 

Год издания: 

Two new Oracle instruction and resource titles from Osborne/McGraw-Hill are indispensable additions to personal and professional reference collections. Oracle Database 10g: A Beginner's Guide is the collective effort of Oracle experts Ian Abramson, Michael Abbey and Michael Corey. Oracle Database 10g provides neophytes with the fundamental concepts of Oracle Database 10g administration and programming. Through self-paced tutorials, readers will learn about database essentials, the role of the administrator, and large database features. Oracle Database 10g includes an in-depth introduction to SQL, PL/SQL, Java, and XML programming.


Fiat Tipo and Tempra 1988-1996. Repair Manual – service guide Fiat Tipo and Tempra 1988-1996. Repair Manual – service guide

Автор: Коллектив авторов

Год издания: 

Инструкция по ремонту и обслуживанию моделей Fiat Tipo и Tempra. Дано описание всех узлов и агрегатов и советы по их эксплуатации и техобслуживанию. Чертежи, таблицы и схемы электрооборудования. Fiat Tipo - автомобиль итальянской компании Фиат. Был разработан дизайн студией IDEA. Выпускался с 1988 года по 1996 год.


Guide to self-repairing car bodies, in eBook Guide to self-repairing car bodies, in eBook

Автор: Монолит

Год издания: 

Content

Introduction

  • Body / frame and body structure
  • General information about replacing body panels
  • Safety first
Maintenance
  • Caring for paint
  • Recovery
  • Antirust treatment and priming
Overview of damage types and their recovery
  • Determination of severity of damage
  • The choice between repair and replacement
Tools and equipment
  • Tools and equipment
  • Equipment
Elimination of minor body damage
  • Eliminating scratches from paintwork
  • Elimination of minor dents
  • Restoration of areas exposed to minor corrosion
  • Repair of plastic body parts
Restoring a body that has serious damage
  • Types of tin work
  • Putties
  • Correction of significant corrosion damage
  • Glass fiber recovery methods
  • Correcting the stiffness of the bearing body by stretching
Replacement of body panels
  • Introduction
  • Body parts fastened on bolts
  • Welded panels
  • Adhesive body elements
  • Coupling of body panels
Preparing for painting
  • Preparation of old paint
  • Removing paintwork preparing for painting
  • Application of primer
  • Masking panels
Body painting
  • Painting equipment
  • Maintenance of the spray gun
  • Types of paint
  • Staining procedure
  • Prophylaxis and a technique of elimination of the defects arising at painting and drying
Doors and glasses
  • Replacement and adjustment of doors
  • Repair, replacement and installation of glasses
Facing and body accessories
  • General information
  • Removing and installing body linings and accessories
  • Removing and installing outdoor lighting
  • Removing and installing emblems and moldings
Welding
  • General information
  • Types of welding
  • Welding with a consumable electrode in shielding gas
  • Oxygen-acetylene welding
  • Soldering
A dictionary of terms used in the performance of body repair


Welding guide, in eBook Welding guide, in eBook

Автор: Монолит

Год издания: 

Content

Introduction

  • Definition of the welding process
  • Development of modern welding
  • Welding these days
Types of welding
  • How it works
  • Metal alloys
  • Oxygen-acetylene welding
  • Electric arc welding
  • Apparatuses for arc welding with a consumable electrode in an inert gas environment
  • Arc welding with tungsten electrode in an inert gas environment
  • Work cycles
  • Plasma welding and cutting
  • Practice and training
Oxygen-acetylene welding / cutting
  • Basics of gas welding technology
  • Equipment
  • Getting Started with oxygen-acetylene welding equipment
  • Flame adjustment
  • Gas welding
  • Welding with filler rod
  • Inspection of welds
  • Soldering
  • Oxygen-acetylene cutting
  • Heating with an oxygen-acetylene burner
Electric arc welding
  • Comparison of work cycles
  • Units working on AC, DC or universal?
  • Arc welding technology
  • Precautions
  • Start of electric arc welding
  • Connection types
  • Electrode selection
Welding with a metal electrode in an inert gas environment
  • Acquisition of aggregates for welding with a metal electrode in an inert gas environment
  • Selection of shielding gas
  • Selecting a wire electrode
  • Welding training with a metal electrode in an inert gas environment
Welding with a tungsten electrode in an inert gas environment
  • Equipment
  • Technology in action
  • Aluminum welding with tungsten electrode in an inert gas environment
Plasma welding / cutting
  • Plasma welding
  • Plasma cutting
  • Selection of equipment for plasma cutting
  • Using plasma cutting
Safety and equipment for the workshop Making a truck trailer to a car

Glossary of terms related to welding