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The manual is for foreigners who begin to learn Russian from scratch. The major difference this manual from all textbooks on the Russian language for foreigners is the absence of unnecessary information and unnecessary words. If you learn all the models presented in this manual, you will be able to talk with native speakers of Russian without any problems, and by the way and without efforts you will learn the grammar well.

30 tutorials and more than 100 exercises in chemoinformatics, supported by online software and data sets Chemoinformatics is widely used in both academic and industrial chemical and biochemical research worldwide. Yet, until this unique guide, there were no books offering practical exercises in chemoinformatics methods. Tutorials in Chemoinformatics contains more than 100 exercises in 30 tutorials exploring key topics and methods in the field. It takes an applied approach to the subject with a strong emphasis on problem-solving and computational methodologies. Each tutorial is self-contained and contains exercises for students to work through using a variety of software packages. The majority of the tutorials are divided into three sections devoted to theoretical background, algorithm description and software applications, respectively, with the latter section providing step-by-step software instructions. Throughout, three types of software tools are used: in-house programs developed by the authors, open-source programs and commercial programs which are available for free or at a modest cost to academics. The in-house software and data sets are available on a dedicated companion website. Key topics and methods covered in Tutorials in Chemoinformatics include: Data curation and standardization Development and use of chemical databases Structure encoding by molecular descriptors, text strings and binary fingerprints The design of diverse and focused libraries Chemical data analysis and visualization Structure-property/activity modeling (QSAR/QSPR) Ensemble modeling approaches, including bagging, boosting, stacking and random subspaces 3D pharmacophores modeling and pharmacological profiling using shape analysis Protein-ligand docking Implementation of algorithms in a high-level programming language Tutorials in Chemoinformatics is an ideal supplementary text for advanced undergraduate and graduate courses in chemoinformatics, bioinformatics, computational chemistry, computational biology, medicinal chemistry and biochemistry. It is also a valuable working resource for medicinal chemists, academic researchers and industrial chemists looking to enhance their chemoinformatics skills.

Tutorial: how to crochet an adult slippers from fabric (t-shirt) yarn in English.Tutorial includes 3 basic slippers schemes for size 37—38 EU (6—7 US) (Scheme of right sole, Scheme of left sole and the Scheme top of the slippers), a detailed verbal description of the schemes, 4 additional schemes for increasing/decreasing the size of slippers (

The information necessary for a quick independent mastering of the basics of public speaking is presented briefly and essentially. Specific advice is given: what should be done and what should not be done in any case. The book is primarily necessary for those who plan to make a career in any field.The author is a scientific researcher, has extensive experience in managing teams and public speaking.

Just for Christmas?Pretty, proper Anna Miller has all the makings of a respectable Amish housewife. But the outside world has always beckoned. So, when a handsome FBI agent needs help caring for his infant twin nephews right before Christmas, Anna jumps at the opportunity. Maybe she can finally discover where she truly belongs.Special agent Colt Asher lives for his job. So, he's surprised when an unexpected week as a hands-on uncle fills his life with meaning. Of course, it helps that the babies' gorgeous nanny is unlike any woman the love-'em-and-leave-'em lone wolf has ever known. But Anna's taste of freedommight send her straight back to her village. Or, if Colt lets her, Anna might just be his Christmas wish come true…