Скачать книгу - Implementing CDISC Using SAS



For decades researchers and programmers have used SAS to analyze, summarize, and report clinical trial data. Now Chris Holland and Jack Shostak have updated their popular <i>Implementing CDISC Using SAS</i>, the first comprehensive book on applying clinical research data and metadata to the Clinical Data Interchange Standards Consortium (CDISC) standards. <p> <i>Implementing CDISC Using SAS: An End-to-End Guide, Revised Second Edition</i>, is an all-inclusive guide on how to implement and analyze the Study Data Tabulation Model (SDTM) and the Analysis Data Model (ADaM) data and prepare clinical trial data for regulatory submission. Updated to reflect the 2017 FDA mandate for adherence to CDISC standards, this new edition covers creating and using metadata, developing conversion specifications, implementing and validating SDTM and ADaM data, determining solutions for legacy data conversions, and preparing data for regulatory submission. The book covers products such as Base SAS, SAS Clinical Data Integration, and the SAS Clinical Standards Toolkit, as well as JMP Clinical. Topics included in this edition include an implementation of the Define-XML 2.0 standard, new SDTM domains, validation with Pinnacle 21 software, event narratives in JMP Clinical, STDM and ADAM metadata spreadsheets, and of course new versions of SAS and JMP software. The second edition was revised to add the latest C-Codes from the most recent release as well as update the make_define macro that accompanies this book in order to add the capability to handle C-Codes. The metadata spreadsheets were updated accordingly. <p> Any manager or user of clinical trial data in this day and age is likely to benefit from knowing how to either put data into a CDISC standard or analyzing and finding data once it is in a CDISC format. If you are one such person–a data manager, clinical and/or statistical programmer, biostatistician, or even a clinician–then this book is for you.


Photoshop CS2 Raw: Using Adobe Camera Raw, Bridge, and Photoshop to Get the Most Out of Your Digital Camera Photoshop CS2 Raw: Using Adobe Camera Raw, Bridge, and Photoshop to Get the Most Out of Your Digital Camera

Автор: Aaland Mikkel

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The RAW file format is the uncompressed data file captured by a digital camera's electronic sensor. When your camera saves an image in RAW format, settings like white balance, sharpening, contrast and saturation are not applied to the image but are saved instead in a separate header. Because RAW files remain virtually untouched by in-camera processing, they are essentially the digital equivalent to exposed but undeveloped film. This makes RAW an increasingly popular format with amateur and professional digital photographers, because it affords greater flexibility and control during the editing process-if you know how to work with RAW files. Most digital camera manufacturers supply their own software for converting RAW data, as do some third party vendors. Increasingly, however, the RAW converter of choice is a plug-in included in the latest version of Adobe Photoshop, the most popular and widely-used digital image editing tool in the world. Adobe Photoshop CS2 is emerging as the best place to edit RAW images, and the best way to master this new format is with Photoshop CS2 RAW. An important book dedicated to working with RAW in Photoshop, this comprehensive guide features a unique design that helps readers grasp the subject through visual instruction and prompts. The entire RAW process is explored, from shooting to using the Adobe plug-in converter and new Bridge navigation software. The primary focus of Photoshop RAW is, as the title suggests, Photoshop editing technique: automating RAW workflow, correcting exposures, extending exposure range, manipulating grayscale and working with the new DNG (Digital Negative) open standard that Adobe supports. Presented by photographer Mikkel Aaland, a pioneer of digital photography and author of eight books, including O"Reilly"s Photoshop for the Web and the award-winning Shooting Digital, Photoshop CS2 RAW investigates and instructs in an accessible visual style. Required reading for professionals and dedicated photo hobbyists alike.


The Art of Amusing The Art of Amusing

Автор: Frank Bellew

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Implementing Missionary Activity. Theory and Practice Implementing Missionary Activity. Theory and Practice

Автор: Igor Vladimirovich Yanshin

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The manual is designed to help full-time ministry workers and lay-people understand legislation concerning missionary activity, and how to conduct oneself while preaching, or engaging in outreach activities.


Great musicians and their amusing stories Great musicians and their amusing stories

Автор: Nadia Koval

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This book is a kind of a door, through which you will get to know the famous musicians via their relationships with the surrounding world and their colleagues. Here you will learn how the musicians spoke about one another, whom they loved and whom they did not like, with whom they were friends and with whom they competed. In addition, you will learn how their music is born and the beneficial impact it has on us.


Martyn and amusing astrology. We become what we think Martyn and amusing astrology. We become what we think

Автор: Alex Tenchoy

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It is very important to generate a good attitude, a good heart, as much as possible. From this, happiness in both the short term and the long term for both yourself and others will come. Dalai Lama XVI