Repensar los museos y centros de ciencias
Автор: Cesar A. Dominguez
Год издания: 0000
El libro versa sobre el proceso de renovacion de los museos y centros de ciencias (MCC), y aporta una reflexion sobre la importancia de estos espacios dentro del entorno social, economico y cultural en el que vivimos. Idealmente, el resultado de esta reflexion deberia guiar el proceso de renovacion para ajustarlo a nuestra realidad y alcanzar cabalmente los objetivos de fomentar el desarrollo de una cultura cientifica y del pensamiento critico en la sociedad. A pesar de lo atractivo que parecen estos objetivos, es importante darnos cuenta de que la consecucion de estas metas tiene consecuencias que van mas alla de la aspiracion subjetiva de incrementar la cultura de la poblacion.
Centrosomes in Development and Disease
Автор: Erich Nigg A.
Год издания:
Discovered over a century ago, the centrosome is the major microtubule organizing center of the animal cell. It is a tiny organelle of surprising structural complexity. Over the last few years our understanding of the structure and composition of centrosomes has greatly advanced, and the demonstration of frequent centrosome anomalies in most common human tumors has sparked additional interest in the role of this organelle in a broader scientific community. The centrosome controls the number and distribution of microtubules – a major element of the cell cytoskeleton – and hence influences many important cellular functions and properties. These include cell shape, polarity, and motility, as well as the intracellular transport and positioning of various organelles. Of particular interest, centrosome function is critical for chromosome segregation and cell division. This book is meant to summarize our current knowledge of the structure, function and evolution of microtubule organizing centers, primarily centrosomes. Emphasis is on the role of these organelles in development and disease (particularly cancer).