Найти книгу: "Alzheimer"

Your sensitive, authoritative guide to Alzheimer's and dementia If a loved one has recently been diagnosed with dementia or Alzheimer's disease, it's only natural to feel fraught with fear and uncertainty about what lies ahead. Fortunately, you don't have to do it alone. This friendly and authoritative guide is here to help you make smart, informed choices throughout the different scenarios you'll encounter as a person caring for someone diagnosed with dementia or Alzheimer's disease. From making sense of a diagnosis to the best ways to cope with symptoms, Alzheimer's and Dementia For Dummies is the trusted companion you can count on as you navigate your way through this difficult landscape. Affecting one's memory, thinking, and behavior, dementia and Alzheimer's disease can't be prevented, cured, or slowed—but a diagnosis doesn't mean you have to be left helpless! Inside, you'll find out how to make sense of the symptoms of dementia and Alzheimer's disease, understand the stages of the illnesses, and, most importantly, keep your loved one safe and comfortable—no matter how severe their symptoms are. Find out what to expect from Alzheimer's and dementia Discover what to keep in mind while caring for someone with Alzheimer's or dementia Uncover symptoms, causes, and risk factors of Alzheimer's and dementia Learn the critical information needed to help manage these illnesses Whether you're new to caring for a person affected by Alzheimer's or dementia or just looking for some answers and relief on your journey, this is the trusted resource you'll turn to again and again.

BACE inhibitors and their use in the treatment of Alzheimer's Disease BACE (?-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. This book details the story of the discovery of BACE and its role in AD and comprehensively discusses: The development of BACE inhibitors as therapeutics for Alzheimer's disease The research that led to the identification of BACE New BACE inhibitors currently being clinically tested ADME (absorption, distribution, metabolism, excretion) and clinical trial design—topics not addressed in current field literature Cutting-edge technology such as high-throughput screening, structure-based drug design, and QSAR in context of BACE inhibitors and Alzheimer's drug discovery Other approaches to BACE inhibition based on interaction with the precursor protein APP By enhancing the reader's understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer's research—and inspire new approaches to treatment of AD.

The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field Summarizes the most recent developments in the fields of Alzheimer's disease and dementia Brings together articles from a prominent and international group of contributors Encompasses a unique range of topics, combining basic molecular perspectives and cognitive neurosciences

Winner of the 2002 BMA Popular Medicine Book Prize: This is a haunting literary and scientific examination of Alzheimer’s disease and the race to find a cure.‘A truly remarkable book – the definitive work on Alzheimer’s, both in social and medical terms, “The Forgetting” is incisive, humane, never ponderous, full of dry humour and brilliantly written with quiet, unpretentious authority. As a layman with personal experience of “caring” for an Alzheimer’s sufferer I am well aware of the stages of the disease and its prognosis and ending. Shenk is excellent on all these, and in his reflections on memory and the individual, and the individual’s response to the progress of the disease. I can’t imagine a book on Alzheimer’s being better researched and understood, or presented with greater sympathy.’ John BayleyIn 1906 Alois Alzheimer dissected and examined the cerebral cortex of Auguste D’s brain and became the first scientist in medical history to link a specific brain pathology to behavioural changes. The disease named after him, turns otherwise active and healthy people into living ghosts. It is a rare condition for those in their 40s and 50s but 10% of the 65+ population suffers from it and 50% of the 85+. It is longevity’s revenge and as the baby boom generation drifts into its elderly years the number of Alzheimer’s victims is expected to quadruple, making it the fastest-growing disease in developed countries.As Adam Phillips writes in his foreword ‘This remarkable book will radically change our notions of looking after people and our assumptions about independence. Out of fear of mortality we have idealised health and youth and competence. “The Forgetting” reminds us among many other things that there is more to life than that.’Shenk’s history of Alzheimer’s is both poignant and scientific, grounded by the fundamental belief that memory forms the basis of our selves, our souls, and the meaning in our lives.

Cfare eshte kjo semundje? Cilat jane shkaqet? Cfare pasojash sjell? Zbuloji te gjithe celesat e semundjes se Alzheimerit. Alzheimeri eshte nje semundje qe po shtohet persa i perket numrit te rasteve te prekura gjate viteve te fundit, dhe ne kete aspekt kane lindur shume pyetje ne momentin kur nje person apo nje i aferm njihet me diagnozen, si per shembull: cfare eshte Alzheimeri? Cili eshte shkaku? A ka nje trajtim te tij? Si zhvillohet semundja? Cfare pasojash sjell ne jeten e perditshme? Cilat jane efektet psikologjike mbi pacientin? Hapet keshtu nje mori pyetjesh qe tentojne te ulin pasigurine qe shkaktohet kur arrin te marresh vesh se vuan nga nje semundje cdo here e “me te hasur” dhe me te veshtire, per te cilen dihen tashme edhe zhvillimet e fundit shkencore, dhe kjo pasiguri ndodh jo vetem per shkak te nje pjese te madhe te kompleksitetit te gjuhes teknike qe perdoret, por edhe sepse keto zhvillime te fundit vijne zakonisht tek specialistet nepermjet mbledhjeve dhe kongreseve ku shperndahet nje informacion i tille. Objektivi: Objektivi i ketij libri elektronik eshte qe te sherbeje si model fillestar per ata persona qe vuajne vete ose kane nje te aferm ne familjen e tyre qe vuan nga semundja e ALZHEIMERIT. Ky liber ka per qellim te prezantoje ne forme sa me te qarte rezultatet e kerkimeve te fundit mbi semundjen e Alzheimerit, duke u dhene pergjigje tre pyetjeve thelbesore, si nga kendveshtrimi i pacientit ashtu edhe i familjareve te tij, duke filluar nga me kryesorja: cfare eshte Alzheimeri? Cilat jane shkaqet? Dhe cfare pasojash sjell ne jeten e pacientit dhe te afermve te tij? Ky liber u adresohet: – Specialisteve te shendetit qe deshirojne te thellojne diagnostikimin dhe trajtimin e semundjes se Alzheimerit. – Profesoreve qe duan t’u ofrojne studenteve te tyre nje informacion te azhornuar mbi semundjen e Alzheimerit. – Kujtdo qe eshte diagnostikuar me semundjen e Alzheimerit dhe te afermve te tij/saj ne menyre qe t’i mesoje se si te veprojne per t’i bere balle kesaj semundje. Ceshtjet Si me poshte do te gjeni secilen nga ceshtjet thelbesore qe trajtohen ne kete punim: – Perkufizimi i Alzheimerit: pavaresisht gjithe asaj qe eshte degjuar te flitet per Alzheimerin, per shume njerez eshte akoma i panjohur. – Shkaqet e Alzheimerit: zbulo shkakun e Alzheimerit, duke e njohur me mire me qellim parandalimi. – Pasojat e Alzheimerit: si per jeten e personit qe eshte diagnostikuar me semundjen e Alzheimerit, ashtu edhe per te afermit e tij/saj.