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Chronic total occlusions (CTO) are common, and found in approximately one third of patients with significant coronary artery disease who undergo angiography. Over the past 20 years, CTO lesions have represented the most difficult anatomy for treatment – with lower success rates and higher complication rates. Chronic Total Occlusions provides interventionalists insight into the world of CTOs with introductory chapters that describe the pathology and indications of CTOs along with a review of clinical trials. Imaging modalities including CT angiography, magnetic navigation wire, and IVUS guided recanalization of CTO are also introduced, together with information on new wires technology and devices for CTOs. With numerous illustrations of these devices, technologies, and strategies to improve the CTO success rate, this clinical guide, headed up by Ron Waksman, will prove to be the ideal companion for interventional cardiologists and cardiac surgeons who are required to perform angioplasty and coronary stenting.

A collection of the best moments from the record-breaking ‘Ricky Gervais Show’ podcasts with additional musings and original drawings by Karl Pilkington, the show’s unlikely star.Karl Pilkington, the Confucian-like savant of the ‘Ricky Gervais Show’, has led an extraordinary and curiously individual life. As a kid growing up in Manchester he regularly missed school to accompany his parents on caravanning holidays and left without collecting his exam results: his family weaned him well.Pilkington’s is a brilliant mind, locked inside a perfectly round head, and uncluttered by the unhelpful constraints of logic or common sense; factors that have led him to such dazzling insights as ‘you never see old men eating Twix bars’ or that the ‘Diary of Anne Frank’ was ‘an Adrian Mole sort of thing’.In this pithy and hilarious book, Karl is in conversation with (the often bewildered) Ricky Gervais and Stephen Merchant, the writers and stars of ‘The Office’ and ‘Extras’, outwitting even these comedy Goliaths with his take on such contentious issues as charity, the lack of Chinese homeless people, reincarnation, the rights of monkeys and favourite superpowers.Featuring Karl's original illustrations, imaginative scribblings, full-colour pictures sent in by fans, and the best conversations of the first twelve podcasts, this is a unique trip into the world of one of our most innovative thinkers, visionaries and prophets, or as Gervais and Merchant know him, ‘the funniest man alive in Britain today’.