Найти книгу: "El endotelio y los marcadores moleculares en la hipertension pulmonar"

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Dedicated to dealing with a challenging disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients. – Latest publication in a fast-moving area of keen clinical interest – Authored by leading international authorities – Builds on success of a respected first edition – Incorporates new data on latest imaging technologies and therapies – Covers both the science and clinical aspects, including presentation, surgical intervention and drug therapy – Includes coverage of both Pulmonary Embolism and Deep Vein Thrombosis

Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention (vaccination) strategies Includes contributions from an international and interdisciplinary group of experts Innate Immunity to Pulmonary Infection is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.

Chronic Obstructive Pulmonary Disease (COPD) is increasing rapidly worldwide and it's predicted that by 2020 it will represent the third leading cause of death. Sadly, this slow-progressing debilitating disease not only affects the individual but also has consequences for the family. More positively, the urgent need to improve the care offered and to raise the public profile of the condition has now been recognised. Healthcare providers play a central role in this, through health education, early diagnosis and better management through all stages of the disease. Managing Chronic Obstructive Pulmonary Disease provides an insight into this debilitative condition. The book aims to develop nurses' and allied health professionals' knowledge and skills in caring for individuals with COPD. It takes the reader on a journey from diagnosis through to end-of-life care and examines: Initial diagnosis and symptom management Smoking cessation Pulmonary rehabilitation The management of acute episodes The role of each member of the multi-disciplinary team Quality of life, including nutrition, fatigue management and leisure activities The future for the care and management of people with the condition. Healthcare professionals from multi-disciplinary teams have contributed to this book to demonstrate that a co-ordinated approach for these patients is required across both primary and secondary care. Managing Chronic Obstructive Pulmonary Disease can be utilised by nurses and allied health professionals caring for patients at all stages of their disease.

First book dedicated to this disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients From the PAH Association, the leading experts in field Incorporates the latest AACP management guidelines Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH